CBD reduces blood pressure

CBD reduces resting blood pressure, as well as blood pressure increases caused by stress.  That’s right, and it helps to remember that CBD is particularly good for anxiety too.

Check out this study by researchers of the University of Nottingham and Oxford, United Kingdom, Royal Derby Hospital Centre, in the Journal of Clinical Investigation Insight.

-Dr. Jake F. Felice

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Dr. Jake Felice to speak on the 2017 Seattle Hempfest medical panel

Did you know that topical cannabis reduces pain in just minutes after application, broadens range of motion, and does not give patients a head high?  Additionally, topical cannabis helps you use less harmful medications such as opiates, and cannabis is one of the safest pain medications that you can use.

I am excited to announce that I will be speaking again this year at Hempfest 2017 the weekend of August 19th at Myrtle Edwards Park in Seattle about the benefits of topical and raw applications of cannabis for chronic pain.

Hempfest is a free event, and speakers will be presenting the most up to date science and information on all things cannabis. For medical, educational, industrial and other topics, check out all of the Hempfest speakers here.

A full list of Hempfest events can be found here.

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Protected: The endocannabinoid system (ECS) for nerds and cannabis geeks

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Dr. Jake on the Marijuana State Report – interview with Barbara Southworth

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Discover the latest views on medical cannabis from Dr. Jake Felice in this radio interview with Barbara Southworth.  Join Dr. Jake and Barbara Southworth as they discuss all things cannabis.  Click here to listen.  Enjoy

Dr. Jake Felice

 

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Dr. Jake opens new office near Santa Barbara, CA

Dr. Jake is happy to announce the opening of his new office in Santa Barbara county, California.  The new office is located just north of Santa Barbara in Goleta, CA.  Dr. Felice is proud to be sharing his office with David Bearman, M.D., one of the most clinically knowledgeable physicians in the U.S. in the field of medicinal marijuana.

Office address:  7394 Calle Real, Suite C, Goleta, CA 93117

#drjake #newoffice #grandopening #goletaca #drjakefelice

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2,700 year old cannabis shaman reveals links to modern day strains

In a remote part of Central Asia, researchers have discovered 789 grams of uniquely preserved cannabis buried 2700 years ago along with a light-skinned, blue-eyed cannabis shaman. The sample contained high levels of THC, and relatively low levels of CBD indicating the possibility that even at this early time in history, cannabis was selectively grown and isolated for medicinal, psychoactive, or spiritual purposes.   

According to the Journal of Experimental Botany, the vegetative material was lightly pounded and was “cultivated for psychoactive purposes”, rather than as fiber, clothing, or as food.  It was likely used for purposes of divination or spirituality.  

The ancient cannabis stash came from plants that were THC dominant.  Wild-type or hemp based cannabis strains would have yielded lower levels of THC and more of a 1:1 ratio of THC to CBD.  About 100 seeds were also found, though unfortunately the genetic material in them was lost as researchers were unable to germinate the seeds.  

Dr. Jake Felice is an accomplished naturopathic physician with extensive experience with cannabinoid therapeutics and medical cannabis consultations.  As a national cannabis brand ambassador he has provided scientific, medical, public relations, product development, and compliance based advice for companies in emerging and existing cannabis markets.  He has consulted for major cannabis companies including Willie Nelson’s brand, Cannabis Basics, Medical Marijuana 411, Seattle Central College, and The Academy of Cannabis Science.  Additionally, he provides ongoing industry training for cannabis professionals in Washington State which are required by law for professionals to obtain medical marijuana consultant certification through the Washington State Department of Health.

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The endocannabinoid system (ECS) is the Internet of our Body

Researchers only recently discovered the endocannabinoid system (ECS), which in many ways resembles the internet of our body. Cells can use it as a kind of email since the ECS allows individual cells to send specific information to other cells in our body. This system helps cells coordinate our immune response for example, and enables the different systems of our body work together.

The endocannabinoid system helps our body organize itself, enabling cells to communicate better, creating and maintaining physiologic balance. It homeostatically regulates all body systems: (nervous, digestive, immune, cardiovascular, endocrine, musculoskeletal, reproductive).

The foundations of the modern endocannabinoid system developed 600 million years ago to help single cell organisms manage the increased demand for information processing required to help single cells evolve into more complex multi-cellular organisms. Cells needed a way to talk to each other to share information and organize themselves into more complex bodies in this early chaotic environment. Multicellular organisms developed the ECS to help manage the flow of information between and within different cells so that individual cells in newly evolving bodies could share resources, protect themselves from harm, and prevent damage to their molecular machinery.

The ECS for example became a central mediator for how the earliest complex organisms reduced harm from things such as a lack of oxygen to their biological systems. Also, the ECS developed biological coordination to help individual cells share nutrition and energy with and between other cells in these newly evolving bodies. In complex biological systems such as humans, this ECS coordination of information prevents disease, and maintains the flow of information between cells.

Chronic disease both causes and results from biological dysfunction in the body. Appropriate cannabis use reduces harm caused by stress, by physiologic imbalances in chronic disease, and particularly in conditions and symptoms that increase as we age. The broad therapeutic potential of using cannabis to help the body balance its own ECS is just beginning to be realized, and major universities and pharmaceutical companies around the world are aggressively engaging in cannabinoid research.

The ECS maintains health and balance not only between different cells, but also within each single cell. Inside single cells, the ECS helps control basic metabolic functions such as sugar metabolism. Between individual cells, the ECS also regulates communication between our immune systems and our nervous systems. For example, when an immune cell needs to alert brain or nerve cells, it can send a biochemical email that functions through the endocannabinoid system. However during disease, a breakdown in ECS communication can disrupt this information flow, resulting in disease or death of the organism.

-Dr. Jake

Dr. Jake Felice is an accomplished naturopathic physician with extensive experience with cannabinoid therapeutics and medical cannabis consultations.  As a national cannabis brand ambassador he has provided scientific, medical, public relations, product development, and compliance based advice for companies in emerging and existing cannabis markets.  He has consulted for major cannabis companies including Willie Nelson’s brand, Cannabis Basics, Medical Marijuana 411, Seattle Central College, and The Academy of Cannabis Science.  Additionally, he provides ongoing industry training for cannabis professionals in Washington State which are required by law for professionals to obtain medical marijuana consultant certification through the Washington State Department of Health.  

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Dr. Jake Felice speaking at the 2016 Seattle Hempfest medical panel

Did you know that topical cannabis reduces pain in just 20 minutes after application, broadens range of motion, and does not give patients a head high. Additionally, topical cannabis helps you use less harmful medications such as opiates, and cannabis is one of the safest pain medications that you can use.

00-Seattle-Hempfest-Festival-Main-Stage1-1024x683I am excited to announce that I will be speaking again this year at Hempfest 2016 the weekend of August 19th at Myrtle Edwards Park in Seattle about the benefits of topical and raw applications of cannabis for chronic pain.

Hempfest is a free event, and speakers will be presenting the most up to date science and information on all things cannabis. For medical, educational, industrial and other topics, check out all of the Hempfest speakers here.

I will be participating in the medical panel on Saturday, August 20 at 11 AM at the Hemposium Music Stage, and on Sunday, August 21 at 1:45 PM at the Seeley Stage, and at 2:45 PM.

A full list of Hempfest events can be found here.

 

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Dr. Jake to discuss cannabis at Port Townsend Chamber of Commerce

cod-david-conklinDr. Jake Felice will be speaking at the Chamber of Commerce in Port Townsend, WA on Tuesday, August 2nd at noon at the Fort Worden CommonsUS_CoC_LogoDr. Felice will be discussing medical cannabis as well as various aspects of Washington’s emerging marijuana industry.  Other members of the panel include attorney Nicole Li of The Li Law Firm, as well as Kody McConnell of Chimacum Cannabis, and Ellen Frick of Sea Change Cannabis.

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Does CBD convert to THC in the stomach? And what does this mean for the world of cannabis?

It appears that stomach acid can convert CBD to THC at low levels according to a study in the Journal of Forensic Toxicology.  This has implications for patients and marijuana consumers who consume CBD edibles, as well as those who must take drug tests for work and believe that their CBD products ensure that they will not test positive.  It also poses potential problems for DUI’s for folks using “CBD only” edibles.

I have previously told my patients that it was OK to take ultra low-THC/high-CBD products orally, and that these would not cause a positive on a urinalysis since these products contain next to no levels of THC.  This can no longer be assumed.  This data could have repercussions for product development for CBD products in the marijuana industry.  One of the biggest areas I see would be in the development of topical CBD as this method of delivery should not convert the CBD to THC since there would be no exposure to stomach acids with transdermal CBD.

This conversion has been reproduced from another study from the journal Cannabis and Cannabinoid Research:

“Gastric fluid without enzymes converts CBD into the psychoactive components D9-THC and D8-THC, which suggests that the oral route of administration may in-crease the potential for psychomimetic adverse effects from CBD.”

What’s interesting is that CBD is also being converted to CBN in gastric juice.  It has been observed in the journal Epilepsy and Behavior that pediatric patients receiving oral CBD will often experience fatigue and sleepiness.  These effects have been attributed to THC by the authors at the Journal of Toxicology, though they could also be related to CBN effects.  Clearly more research is needed to see if this may be clinically significant.

Yours in health,

-Dr. Jake Felice, CannabisMatrix.com

 

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